"The study focused on unintentional drug overdoses, and the number increased by 110 percent," said Kay Sanford, the study's primary investigator and a department epidemiologist.
In 2001, the accidental overdose rate rose to 7.73 per 100,000 people from 1999's rate of 5.54 per 100,000.
Most of North Carolina's unintentional drug-related deaths were from prescription narcotics, methadone in particular, Sanford said. Methadone is most common in substance abuse clinics, but the researchers found these clinics were not the major source of the drug, she said.
The study found that the average age of death from accidental overdose was 39 years old. "This suggests that they are not first-time users," Sanford said.
According to the study, the number of deaths in men is higher, but the number of deaths in women increased by 210 percent during the study's time frame.
Heavily populated counties such as Mecklenburg had the most deaths from accidental overdoses, but smaller rural counties such as Yancey had the highest mortality rates.
The reasons for the increase in accidental overdoses are unclear.
Sanford said the increases could be attributed to rising substance abuse or more drugs on the streets. "There are many things that have changed. ... This is such a complex issue."
The epidemic has gotten so severe that the Centers for Disease Control and Prevention has taken notice and is working with the department to examine the increase, she said.